Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds

Solid phase syntheses of the OF4949 derivs. I (R = H, CH2CONH2) and II (R1 = H, R2 = H, NH2; R1 = NH2, R2 = H) were performed via protection/deprotection of tyrosine side chains on a support, and SNAr macrocyclization reactions. [on SciFinder (R)]


Published in:
Tetrahedron Letters, 38, 19, 3345-3348
Year:
1997
Keywords:
Note:
CAN 127:34501
34-3
Amino Acids, Peptides, and Proteins
Department of Chemistry,Texas A and M University, College Station,TX,USA.
Journal
0040-4039
written in English.
190710-91-9P Role: BYP (Byproduct), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 163395-24-2 Role: RCT (Reactant), RACT (Reactant or reagent) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 107140-32-9DP (OF4949 III); 190710-87-3P; 190710-88-4P; 190710-89-5P; 190710-90-8P Role: SPN (Synthetic preparation), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds)
Laboratories:




 Record created 2010-11-25, last modified 2018-03-17


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