Inhibitory salt effect on the SNAr based macrocycloetherification of a linear diarylheptanoid

Salt effects exerted on the cycloetherification of linear diarylheptanoid 3-OH-4-MeOC6H3(CH2)2COCMe2CO(CH2)2C6H3-3-F-4-NO2 were investigated. Both salting-in and salting-out alkali salts were found to inhibit the macrocyclization. Ion-pairing exchange was proposed to account for the exptl. observations. [on SciFinder (R)]


Published in:
Synlett, 3, 412-414
Year:
2000
Keywords:
Note:
CAN 132:347278
22-5
Physical Organic Chemistry
Institut de Chimie des Substances Naturelles, CNRS,Gif-sur-Yvette,Fr.
Journal
0936-5214
written in English.
7447-40-7 (Potassium chloride); 7447-41-8 (Lithium chloride); 7550-35-8 (Lithium bromide); 7647-14-5 (Sodium chloride); 7789-24-4 (Lithium fluoride); 7791-03-9 (Lithium perchlorate); 13755-29-8 (Sodium tetrafluoroborate) Role: CAT (Catalyst use), USES (Uses) (inhibitor; inhibitory salt effect on the SNAr-based macrocycloetherification of a linear diarylheptanoid); 6674-22-2 (DBU); 7789-23-3 (Potassium fluoride); 13400-13-0 (Cesium fluoride) Role: CAT (Catalyst use), USES (Uses) (inhibitory salt effect on the SNAr-based macrocycloetherification of a linear diarylheptanoid); 269733-58-6 Role: PEP (Physical, engineering or chemical process), RCT (Reactant), PROC (Process), RACT (Reactant or reagent) (inhibitory salt effect on the SNAr-based macrocycloetherification of a linear diarylheptanoid); 269733-59-7P Role: SPN (Synthetic preparation), PREP (Preparation) (inhibitory salt effect on the SNAr-based macrocycloetherification of a linear diarylheptanoid); 1643-19-2 (Tetrabutylammonium bromide) Role: CAT (Catalyst use), USES (Uses) (neutral agent; inhibitory salt effect on the SNAr-based macrocycloetherification of a linear diarylheptanoid)
Laboratories:




 Record created 2010-11-25, last modified 2018-03-17


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