Infoscience

Journal article

Rapid access to tetracyclic ring system of lennoxamine type natural product by combined use of a novel three-component reaction and Pummerer cyclization

From readily available allylamine, aldehyde and isocyanoacetamide, a three-component reaction followed by a Pummerer cyclization provided tetracyclic ring systems [6-7-5-6 (I)and 6-6-5-6 (II)] in excellent overall yields. [on SciFinder (R)]

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