Infoscience

Journal article

A short enantioselective synthesis of protected L-3-hydroxy-4-methoxy-5-methyl phenylalanine and its corresponding aldehyde - a common subunit of ecteinascidin-743, safracin and congeners

An asym. synthesis of appropriately protected L-3-hydroxy-4-methoxy-5-Me phenylalanine from 3-methylcatechol is described featuring a key enantioselective alkylation step. [on SciFinder (R)]

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