Journal article

A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications

A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2-dihydro(iso)quinolines, e.g., I, was developed using alpha -isocyano-beta -Ph-propionamide as an isonitrile input. The structure of this multicomponent adduct was further diversified taking advantage of the rich chem. of oxazole. [on SciFinder (R)]


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