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review article
Regulatory elements and expression profiles
There has been steady progress in the computational analysis of transcription control regions, but current methods of predicting the gene regulatory features of noncoding sequences are still not accurate enough to be useful in automatic genome annotation. Therefore, detailed information on the expression patterns of newly sequenced genes is more likely to come from microarray-based high-throughput mRNA quantitation technologies, which have made revolutionary progress over the past few years and are now ready for genome-wide application. Future solutions to the regulatory element prediction problem may be found by the combined analysis of genome sequence and expression data.
Type
review article
Authors
Publication date
1999
Publisher
Published in
Volume
9
Issue
3
Start page
400
End page
7
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 9, 2010
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