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review article

Cellular oscillators: rhythmic gene expression and metabolism

Schibler, Ueli
•
Naef, Felix  
2005
Current opinion in cell biology

Many biological processes are driven by biological clocks that, depending on the frequency they generate, are classified into ultradian, circadian and infradian oscillators. In virtually all light-sensitive organisms from cyanobacteria to humans, a circadian timing system adapts cyclic physiology to geophysical time. Recent evidence suggests that even in mammals circadian oscillators function in a cell-autonomous manner. In yeast, an ultradian oscillator regulates cyclic respiratory activity and global gene expression. Circadian oscillators and the ultradian yeast respiratory clock share at least four properties: they follow limit-cycle kinetics, interweave with cellular metabolism, are temperature-compensated and influence the cell division clock.

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Type
review article
DOI
10.1016/j.ceb.2005.01.007
Author(s)
Schibler, Ueli
Naef, Felix  
Date Issued

2005

Publisher

Elsevier

Published in
Current opinion in cell biology
Volume

17

Issue

2

Start page

223

End page

9

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
UPNAE  
Available on Infoscience
November 1, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/56527
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