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  4. Recombinant bacillus Calmette-Guérin as a potential vector for preventive HIV type 1 vaccines
 
research article

Recombinant bacillus Calmette-Guérin as a potential vector for preventive HIV type 1 vaccines

Falk, L. A.
•
Goldenthal, K. L.
•
Esparza, J.
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2000
AIDS research and human retroviruses

In August 1997, the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) convened an expert working group to discuss current strategies for the development of HIV type 1 vaccines. Based on the recent findings of investigators from Japan's National Institute of Infectious Diseases (NIID) in Tokyo using recombinant bacillus Calmette-Guérin (rBCG) as a potential vectored vaccine for HIV, a recommendation was made that further work in this area is a priority. As a result, the working group reconvened in September 1998 to discuss the progress to date with this vaccine approach, as well as areas of related research to assess the feasibility of a BCG-vectored HIV vaccine. This report summarizes the discussions addressing the available scientific data on the potential use of rBCG as a vector for preventive HIV vaccines, the work necessary to move such candidate vaccines into Phase 1 clinical trials, and recommendations targeted at facilitating the long-term development of rBCG-vectored HIV vaccines.

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Type
research article
DOI
10.1089/088922200309421
Author(s)
Falk, L. A.
Goldenthal, K. L.
Esparza, J.
Aguado, M. T.
Osmanov, S.
Ballou, W. R.
Beddows, S.
Bhamarapravati, N.
Biberfeld, G.
Ferrari, G.
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Date Issued

2000

Publisher

Mary Ann Liebert

Published in
AIDS research and human retroviruses
Volume

16

Issue

2

Start page

91

End page

8

Subjects

AIDS Vaccines

•

BCG Vaccine

•

Vaccines, Synthetic

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
UPKIN  
Available on Infoscience
October 19, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/55685
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