Active microfluidic mixer using virtual source-sink pairs for DNA purification

We present an active mixer based on the creation of virtual source-sink pairs in a polydimethylsiloxane (PDMS) chip. Perfect mixing is achieved in only a sub-second time interval for a compact 5 μL mixing volume. This excellent performance is achieved thanks to the implementation of co-rotating vortices inside the mixing chamber by using micro-plumbing technology. A DNA isolation and purification protocol using magnetic beads in the mixing chamber is per-formed on-chip, showing the enhanced DNA binding performance due to active mixing.


Published in:
Proceedings of the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 1841-1843
Presented at:
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), Groningen, Netherlands, October 3 - 7, 2010
Year:
2010
ISBN:
978-0-9798064-3-8
Keywords:
Laboratories:




 Record created 2010-10-15, last modified 2018-03-17


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