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Genomics is providing us with a mass of information about the biochemistry, physiology and pathogenesis of Mycobacterium tuberculosis and Mycobacterium leprae. Comparison of the two genome sequences is mutually enriching and indicates that the M. leprae genome appears to have undergone shrinkage and large-scale gene inactivation, which may account for the exceptionally slow growth of this organism.
Type
review article
PubMed ID
10066528
Authors
Publication date
1999
Published in
Volume
1
Issue
5
Start page
567
End page
571
Subjects
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
September 7, 2010
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