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research article
Genome organization of the anaerobic pathogen Clostridium perfringens
A physical map of the genome of Clostridium perfringens, an important human pathogen, has been established by pulsed-field gel electrophoresis. Recognition sites for six rare-cutting endonucleases were situated on a single circular chromosome of approximately 3.6 million base pairs thus defining 50 arbitrary genetic intervals of between 10 and 250 kilobase pairs. This considerably facilitated the chromosomal localization of some 24 genes and loci for which probes were available and allowed the construction of the genome map of a clostridial species.
Type
research article
PubMed ID
2549543
Authors
Publication date
1989
Volume
86
Issue
17
Start page
6676
End page
80
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
September 7, 2010
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