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research article
On the origin of the boson peak in globular proteins
We study the boson peak phenomenology experimentally observed in globular proteins by means of elastic network models. These models are suitable for an analytic treatment in the framework of Euclidean random matrix theory, whose predictions can be numerically tested oil real protein structures. We find that the emergence of the boson peak is strictly related to an intrinsic mechanical instability of the protein. in close similarity to what is thought to happen in glasses. The biological implications, Of this Conclusion are also discussed by focusing Oil a representation case study.
Type
research article
Web of Science ID
WOS:000244150900033
Authors
Publication date
2007
Publisher
Published in
Volume
87
Start page
631
End page
641
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
March 16, 2010
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