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research article
Diffusion Coefficients of Biomolecules Using Long-Lived Spin States
We report the first observation of long-lived states (LLS) having lifetimes TLLS that exceed the corresponding spin−lattice relaxation times T1 by more than a factor 6 in a protein. Slow diffusion coefficients characteristic of large biomolecules can be determined by combining LLS methods with moderate pulsed field gradients (PFGs) available on commercial probeheads, as the extension of spin memory reduces the strain on the duration and/or strength of the PFGs. No isotope labeling of the biomolecule is necessary.
Type
research article
Web of Science ID
WOS:000267177900010
Authors
Publication date
2009
Published in
Volume
131
Issue
22
Start page
7498
End page
7499
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
December 22, 2009
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