How iron controls iron

Cells regulate iron homeostasis by posttranscriptional regulation of proteins responsible for iron uptake and storage. This requires RNA-binding activity of iron-regulatory proteins, IRP1 and IRP2. Two studies recently published in Science by Vashisht et al. (2009) and Salahudeen et al. (2009) reveal how cells adjust IRP2 activity.


Published in:
Cell Metabolism, 10, 439-441
Year:
2009
Keywords:
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 Record created 2009-11-19, last modified 2018-03-17


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