Diffusion of Single Molecules in Nanochannels

With fluorescence correlation spectroscopy (FCS), the diffusion and concentration of proteins (wheat germ agglutinin) in a nanofluidic system are measured on a single molecule level. By increasing the ionic concentration, the Debye length of the electrical double layer (EDL) decreases altering the strongly enhanced surface interactions of charged proteins in nanochannels. A theoretical model of the transport of charged mole- cules in nanofluidics facilitates the design of future nanochannel applications.


Presented at:
Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009
Year:
2009
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2009-10-27, last modified 2018-03-17

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