Diffusion MR Image Segmentation: Towards Global Brain Connectivity Analysis

The exploration of the human connectome, a term denoting the global structural connectivity of the brain, is accessible to MRI at millimeter and centimeter scales. In this paper, we propose a methodology to map the connectome by constructing normalized whole-brain structural connection matrices derived from diffusion spectrum MRI tractography. Using a template-based approach, we propose a robust method that allows a) the selection of identical cortical regions of interest in different subjects with identification of the associated fiber tracts, b) a straightforward construction and interpretation of anatomically organized whole-brain connection matrices, and c) a statistical inter-subject comparison of brain connectivity.


Published in:
Proceedings of the 10th European Congress of Stereology and Image Analysis
Presented at:
10th European Congress of Stereology and Image Analysis, Milano, June 22-26, 2009
Year:
2009
Publisher:
Societa Editrice Esculapio-Progetto Leonardo, Via Umberto Terracini 30, Bologna, 40131, Italy
Keywords:
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 Record created 2009-05-29, last modified 2018-11-14

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