Hardware-software design of a smart sensor for fully-electronic DNA hybridization detection

This paper describes the design of a smart sensor for label-free detection of DNA hybridization. The sensor is based on a direct electrical transduction principle: it measures impedance variation at the interface between a bio-functionalized electrode and a solution containing the analyte. The smart sensor includes a complete signal conditioning and processing subsystem based on an embedded it-controller We outline the sensor architecture, and we describe in details board-level integration as well as hardware and software implementation and design choices. The accuracy of our embedded solution has been evaluated by comparing it with a high-cost laboratory setup. Moreover, we provide measurements of real sensing structures which demonstrate infield the functionality of our system.

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Designers' Forum: Design, Automation and Test in Europe Conference and Exhibition, 198-203
Wehn, N Lindwer, M Heer, C Design, Automation and Test in Europe Conference and Exhibition (DATE 05) MAR 07-11, 2005 Munich, GERMANY

 Record created 2009-05-12, last modified 2018-03-17

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