A new tandem reaction leads to bicyclic cyclohexene derivatives with complete control of the relative configuration of the four chiral centers formed. The high diastereoselectivity is the consequence of an endo-selective Diels-Alder reaction followed by an Ireland-Claisen rearrangement that proceeds via a boat-like transition state. © Georg Thieme Verlag Stuttgart.
Type
research article
Scopus ID
2-s2.0-34547749424
Authors
Soldermann, N.
•
Velker, J.
•
Neels, A.
•
Stoeckli-Evans, H.
•
Neier, R.
Publication date
2007
Published in
Volume
15
Issue
15
Start page
2379
End page
2387
Note
422
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
May 12, 2009
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