Infoscience

Journal article

Towards a planar sample support for in situ experiments in structural biology

Gullo, M.; Akiyama, T.; Frederix, P.; Tonin, A.; Staufer, U.; Engel, A.; de Rooij, N. F.; Frederix, P.L.T.M.
  • Published in: Microelectronic Engineering (ISSN: 01679317), vol. 78-79, num. 1-4, p. 571-574
  • Publication date: 2005

We report about the development of a planar support for biological samples. The aim is to combine AFM and patch-clamp measurements, in order to perform simultaneous measurements of topography and electrical properties of biological membranes. Sub-micrometer apertures have been fabricated using standard MEMS techniques. The electrical quality of the support has been experimentally assessed. © 2005 Elsevier B.V. All rights reserved.

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