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patent
Methods for increasing cellular energy expenditure
2008
The present invention is directed to methods of treating a human for a variety of conditions by administering an agonist of the G protein coupled receptor TGR5. In addition, the invention includes methods for determining whether a test compound is likely to be effective in treating one of these conditions by assaying it for its ability to raise intracellular iodothyronine deiodinase levels or for its ability to bind to and activate TGR5
Type
patent
EPO Family ID
39029466
Inventors
Bianco, A.
•
•
Christoffolete, M.A.
•
Houten, S.
•
Kim, B.W.
•
Larsen, P.R.
•
Watanabe, M.
Note
Applicant(s): Brigham & Womens Hospital [Us]
EPFL units
Patent number | Country code | Kind code | Date issued |
US2008031968 | US | A1 | 2008-02-07 |
Available on Infoscience
April 21, 2009
Use this identifier to reference this record