Methods for increasing cellular energy expenditure

The present invention is directed to methods of treating a human for a variety of conditions by administering an agonist of the G protein coupled receptor TGR5. In addition, the invention includes methods for determining whether a test compound is likely to be effective in treating one of these conditions by assaying it for its ability to raise intracellular iodothyronine deiodinase levels or for its ability to bind to and activate TGR5


Year:
2008
Note:
Applicant(s): Brigham & Womens Hospital [Us]
Other identifiers:
EPO Family ID: 39029466
Patent number(s):
Laboratories:




 Record created 2009-04-21, last modified 2018-03-17


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