Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders

Provided herein are methods and compositions for treating or preventing metabolic disorders, such as obesity and diabetes. Methods may comprise modulating the activity or level of a sirtuin, such as SIRT1 or Sir2. Exemplary methods comprise contacting a cell with a sirtuin activating compound, such as a flavone, stilbene, flavanone, isoflavone, catechin, chalcone, tannin or anthocyanidin, or an inhibitory compound, such as nicotinamide


    Applicant(S): Sirtris Pharmaceuticals Inc [Us]


    Record created on 2009-04-21, modified on 2017-05-12


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