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book part or chapter
Dietary manipulation of mouse metabolism
The maintenance of metabolic homeostasis relies on the balanced intake of nutrients from food. Consequently, diet composition strongly impacts whole-body physiology. Dietary formulations with strong nutrient imbalances can lead to metabolic disorders, with lipids and simple sugars playing a prominent role. This unit describes how diet formulation can be modified to generate mouse models of human metabolic pathologies, and it details methodological procedures linked to dietary manipulations, including caloric restriction and introduction of a test compound
Type
book part or chapter
Authors
Editors
Ausubel, F.M.
•
Struhl, K.
•
Smith, J.A
•
Seidman, J.G.
•
Moore, D.D.
•
Kingston, R.E.
Publication date
2008
Publisher
Published in
Current Protocols in Molecular Biology
Start page
29B.5
Series title/Series vol.
Current Protocols
EPFL units
Available on Infoscience
April 17, 2009
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