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review article
Mouse phenogenomics: the fast track to "systems metabolism"
2005
With the completion of the many genomes, genetics is positioned to meet physiology. In this review, we summarize the coming of "systems metabolism" in mammals through the use of the mouse, as a model system to study metabolism. Building on mouse genetics with increasingly sophisticated clinical and molecular phenotyping strategies has enabled scientists to now tackle complex biomedical questions, such as those related to the pathogenesis of the common metabolic disorders. The ultimate goal of such strategies will be to mimic human metabolism with the click of a mouse.
Type
review article
PubMed ID
16330321
Authors
Publication date
2005
Published in
Volume
2
Issue
6
Start page
349
End page
60
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
April 2, 2009
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