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review article

Mechanisms of pathogen entry through the endosomal compartments

Gruenberg, J.
•
van der Goot, F. G.  
2006
Nature Reviews Molecular Cell Biology

Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregulation and signalling. Because most of these pathways end in lysosomes, an organelle that is capable of killing microorganisms, pathogens have developed remarkable means to avoid interactions with this lytic organelle

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Type
review article
DOI
10.1038/nrm1959
Web of Science ID

WOS:000238618500015

Author(s)
Gruenberg, J.
van der Goot, F. G.  
Date Issued

2006

Published in
Nature Reviews Molecular Cell Biology
Volume

7

Issue

7

Start page

495

End page

504

Note

Author address: Department of Biochemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva, Switzerland

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
VDG  
Available on Infoscience
February 2, 2009
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/34683
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