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review article
Mechanisms of pathogen entry through the endosomal compartments
Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregulation and signalling. Because most of these pathways end in lysosomes, an organelle that is capable of killing microorganisms, pathogens have developed remarkable means to avoid interactions with this lytic organelle
Type
review article
Web of Science ID
WOS:000238618500015
Authors
Publication date
2006
Published in
Volume
7
Issue
7
Start page
495
End page
504
Note
Author address: Department of Biochemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva, Switzerland
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 2, 2009
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