Mechanisms of pathogen entry through the endosomal compartments

Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregulation and signalling. Because most of these pathways end in lysosomes, an organelle that is capable of killing microorganisms, pathogens have developed remarkable means to avoid interactions with this lytic organelle


Published in:
Nat Rev Mol Cell Biol, 7, 7, 495-504
Year:
2006
Note:
Author address: Department of Biochemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva, Switzerland
Other identifiers:
Laboratories:




 Record created 2009-02-02, last modified 2018-03-17


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)