In this paper we propose a novel method which is able to detect and separate audio-visual sources present in a scene. Our method exploits the correlation between the video signal captured with a camera and a synchronously recorded one-microphone audio track. In a ﬁrst stage, audio and video modalities are decomposed into relevant basic structures using redundant representations. Next, synchrony between relevant events in audio and video modalities is quantiﬁed. Based on this co-occurrence measure, audio-visual sources are counted and located in the image using a robust clustering algorithm that groups video structures exhibiting strong correlations with the audio. Next periods where each source is active alone are determined and used to build spectral Gaussian Mixture Models (GMMs) characterizing the sources acoustic behavior. Finally, these models are used to separate the audio signal in periods during which several sources are mixed. The proposed approach has been extensively tested on synthetic and natural sequences composed of speakers and music instruments. Results show that the proposed method is able to successfully detect, localize, separate and reconstruct present audio-visual sources.