An overview of the fission yeast septation initiation network (SIN)

The fission yeast septation initiation network, or SIN, is a signal transduction network that is required for septum formation in Schizosaccharomyces pombe. Its activity is tightly regulated through the cell cycle, to ensure proper co-ordination of mitosis and cytokinesis. SIN signalling requires three protein kinases for its function and is mediated by a ras-superfamily GTPase. We discuss the elements of the SIN and how they are regulated.


Published in:
Biochem Soc Trans, 36, Pt 3, 411-5
Year:
2008
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 Record created 2008-10-21, last modified 2018-03-17


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