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research article
A DMSO-sensitive conditional mutant of the fission yeast orthologue of the Saccharomyces cerevisiae SEC13 gene is defective in septation
2002
Dissection of complex processes using model organisms such as yeasts relies heavily upon the use of conditional mutants. We have generated a collection of fission yeast mutants sensitive to dimethylsulphoxide (DMSO). Among these we have found a mutant in the Schizosaccharomyces pombe orthologue of the Saccharomyces cerevisiae SEC13 gene, which fails to cleave the division septum. Generation of a null allele demonstrates that the S. pombe sec13 gene is essential.
Type
research article
Author(s)
Date Issued
2002
Published in
Volume
511
Issue
1-3
Start page
85
End page
9
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Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
October 21, 2008
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