Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

During the course of evolution, many genes that control the development of metazoan body plans were co-opted to exert novel functions, along with the emergence or modification of structures. Gene amplification and/or changes in the cis- regulatory modules responsible for the transcriptional activity of these genes have certainly contributed in a major way to evolution of gene functions. In some cases, these processes led to the formation of groups of adjacent genes that appear to be controlled by both global and shared mechanisms.


Editor(s):
van Heyningen, V.
Hill, R. E.
Published in:
Long-Range Control of Gene Expression, 6, 175-205
Year:
2008
Publisher:
Elsevier Inc
Laboratories:


Note: The status of this file is: Involved Laboratories Only


 Record created 2008-07-01, last modified 2018-09-13

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