Colinearity and functional hierarchy among genes of the homeotic complexes

Homeotic genes identify structures along the anterior to posterior axis during the development of most animals. These genes are clustered into complexes, and their positions within the cluster correlates with their time of expression and the positions of the anterioposterior boundaries of their expression domains. Functional analyses have revealed that this specific genetic order also coincides with a functional hierarchy among members of these complexes, so that the products of more posterior genes in the cluster tend to be prevalent over those of more anterior genes


Published in:
Trends Genet, 10, 10, 358-364
Year:
1994
Note:
Departement de Zoologie et Biologie Animale, Universite de Geneve, Switzerland
Laboratories:




 Record created 2008-02-27, last modified 2018-03-17


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