000117638 001__ 117638
000117638 005__ 20181203021110.0
000117638 037__ $$aARTICLE
000117638 245__ $$aPrimary structure and embryonic expression pattern of the mouse Hox-4.3 homeobox gene
000117638 269__ $$a1990
000117638 260__ $$c1990
000117638 336__ $$aJournal Articles
000117638 500__ $$aEMBL, Heidelberg, FRG.
000117638 520__ $$aWe report the cloning, genomic localization, primary structure and developmental expression pattern of the novel mouse Hox-4.3 gene. This gene is located within the HOX-4(5) complex, at a position which classifies it as a member of the Hox-3.1 and -2.4 subfamily, the DNA and predicted protein sequences further confirmed this classification. Hox-4.3 has a primary structure characteristic of a Hox gene but, in addition, contains several monotonic stretches of amino acids, one of the 'paired'-like type. As expected from its presence and position within the complex. Hox-4.3 is developmentally expressed in structures of either mesodermal or neurectodermal origin located or derived from below a precise craniocaudal level. However, a very important offset between anteroposterior boundaries within neuroectoderm versus mesoderm derivatives is observed. Like other genes of the HOX-4(5) complex, Hox-4.3 is expressed in developing limbs and gonads, suggesting that 'cluster specificity' could be a feature of the HOX network.
000117638 700__ $$aIzpisua-Belmonte, J. C.
000117638 700__ $$aDolle, P.
000117638 700__ $$aRenucci, A.
000117638 700__ $$aZappavigna, V.
000117638 700__ $$aFalkenstein, H.
000117638 700__ $$g141236$$aDuboule, D.$$0240276
000117638 773__ $$j110$$tDevelopment$$k3$$q733-45
000117638 909C0 $$xU11705$$0252099$$pUPDUB
000117638 909CO $$pSV$$particle$$ooai:infoscience.tind.io:117638
000117638 937__ $$aUPDUB-ARTICLE-1990-004
000117638 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000117638 980__ $$aARTICLE