Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
1994
Abstract
Various structural components of intercellular junctions have recently been found to represent (or be related to) products of tumor-suppressor genes. The tumor-suppressor gene product adenomatous polyposis coli (APC) binds to beta 2-catenin (homologous to the product of Drosophila armadillo), which is cytoplasmically associated with the cell adhesion molecule E-cadherin
Details
Title
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
Author(s)
Huelsken, J. ; Behrens, J. ; Birchmeier, W.
Published in
Current Opinion in Cell Biology
Volume
6
Issue
5
Pages
711-716
Date
1994
Note
Author address: Max-Delbruck-Center for Molecular Medicine, Berlin, Germany
Laboratories
UPHUELSKEN
Record Appears in
Scientific production and competences > SV - School of Life Sciences > ISREC - Swiss Institute for Experimental Cancer Research > UPHUELSKEN - Prof. Huelsken Group
Peer-reviewed publications
Work outside EPFL
Published
Reviews
Peer-reviewed publications
Work outside EPFL
Published
Reviews
Record creation date
2008-02-13