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research article
Osmotic swelling activates intermediate-conductance Cl- channels in human intestinal epithelial cells
1994
During osmotic swelling of a human intestinal epithelial cell line, stepwise closing unitary events of Cl- channels could be observed in cell-attached patches upon application of large positive potentials only when inactivating whole-cell Cl- currents were simultaneously observed. The closing process became faster with increasing positive command pulses. The unitary conductance was around 32 pS at 60 mV, 37 pS at +100 mV, and 47 pS at +140 mV exhibiting outward rectification.
Type
research article
Authors
Publication date
1994
Published in
Volume
44
Issue
4
Start page
403
End page
9
Note
Department of Cellular and Molecular Physiology, National Institute for Physiological Sciences, Okazaki, Japan.
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
December 18, 2007
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