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research article
Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element
We have biochemically and functionally characterized a new transcription factor, NP-TCII, which is present in nuclei from unstimulated T and B lymphocytes but is not found in nonhematopoietic cells. This factor has a DNA-binding specificity similar to that of NF-kappa B but is unrelated to this or other Rel proteins by functional and biochemical criteria. It can also be distinguished from other previously described lymphocyte-specific DNA-binding proteins.
Type
research article
Authors
Lattion, A. L.
•
Espel, E.
•
Reichenbach, P.
•
Fromental, C.
•
•
Israel, A.
•
Baeuerle, P.
•
Rice, N. R.
•
Nabholz, M.
Publication date
1992
Published in
Volume
12
Issue
11
Start page
5217
End page
5227
Note
Swiss Institute for Experimental Cancer Research, Epalinges.
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
December 17, 2007
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