Abstract
The control of telomerase activity at chromosome ends by telomere-binding proteins is critical for telomere length homeostasis. Two recent papers identify TPP1 as a critical mediator of this control. TPP1 forms part of the telomeric shelterin complex while also associating with telomerase, stimulating its activity and processivity.
Details
Title
Telomerase unplugged
Author(s)
Cristofari, G. ; Sikora, K. ; Lingner, J.
Published in
ACS Chemical Biololgy
Volume
2
Issue
3
Pages
155-8
Date
2007
Note
Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
Other identifier(s)
DAR: 10340
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Laboratories
UPLIN
Record Appears in
Scientific production and competences > SV - School of Life Sciences > ISREC - Swiss Institute for Experimental Cancer Research > UPLIN - Prof. Lingner Group
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2007-11-20