Telomerase unplugged

The control of telomerase activity at chromosome ends by telomere-binding proteins is critical for telomere length homeostasis. Two recent papers identify TPP1 as a critical mediator of this control. TPP1 forms part of the telomeric shelterin complex while also associating with telomerase, stimulating its activity and processivity.


Published in:
ACS Chem Biol, 2, 3, 155-8
Year:
2007
Note:
Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
Other identifiers:
Laboratories:




 Record created 2007-11-20, last modified 2018-03-17


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