Infoscience

Journal article

Telomerase unplugged

The control of telomerase activity at chromosome ends by telomere-binding proteins is critical for telomere length homeostasis. Two recent papers identify TPP1 as a critical mediator of this control. TPP1 forms part of the telomeric shelterin complex while also associating with telomerase, stimulating its activity and processivity.

    Note:

    Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.

    Reference

    Record created on 2007-11-20, modified on 2016-08-08

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