Bio-inspired systems borrow three structural principles characteristic of living organisms: multicellular architecture, cellular division, and cellular differentiation. Implemented in silicon according to these principles, our cellular systems are endowed with self-developing mechanisms like configuration, cloning, cicatrization, and regeneration. These mechanisms are made of simple processes such as growth, load, branching, repair, reset, and kill. The hardware simulation and hardware implementation of the self-developing mechanisms and their underlying processes constitute the core of this paper.