Superparamagnetic iron oxide nanoparticle coupled tissue soldering
The invention relates to superparamagnetic iron oxide nanoparticles for use in sutureless thermal mediated tissue fusion. The nanoparticles are dispersed in a biocompatible solder material and heated by application of an alternating electromagnetic field. The invention furthermore relates to a pharmaceutical preparation comprising superparamagnetic iron oxide nanoparticles, preferably with a diameter of below 20 nm, and such nanoparticles coated with an organic compound and/or imbedded in a biocompatible material, for example a soldering agent. The invention likewise relates to the use of superparamagnetic iron oxide nanoparticles for the manufacture of a medicament for use in tissue fusion with an alternating electromagnetic field, and to a method of tissue fusion wherein superparamagnetic iron oxide nanoparticles dispersed in a biocompatible interface material are heated by application of an alternating electromagnetic field.
39539577
Alternative title(s) : (fr) Soudure tissulaire par couplage de nanoparticules d'oxyde de fer superparamagnetiques (en) Super paramagnetic iron oxide nanoparticle coupled tissue soldering
Patent number | Country code | Kind code | Date issued |
WO2008125259 | WO | A3 | 2009-07-30 |
WO2008125259 | WO | A2 | 2008-10-23 |