This communication reports on the growth of highly uniform KNbO3 nanowires exhibiting a narrow diameter distribution around 60 nm and a length-to-width ratio up to 100. The nanowires were prepared by a hydrothermal route, which enables simple, gram-scale production. A systematic study of the synthesized nanowires in terms of the morphological and chemical characteristics was carried out by varying the temperature-pressure conditions and the composition of the starting mixture. The results indicate that highly uniform single-crystalline nanowires form within a narrow window of the ternary phase diagram of KOH-Nb2O5-H2O.