ESI-MS characterisation of protein adducts of anticancer ruthenium(II)-arene PTA (RAPTA) complexes

Electrospray ionization mass spectrometry allows a rapid characterization of the adducts formed between three novel anticancer ruthenium(II)-arene PTA compds. and horse heart cytochrome c or hen egg white lysozyme. Specific information on the nature of the protein-bound metallic fragments and the extent of protein metalation was readily obtained.


Published in:
CHEMMEDCHEM, 2, 5, 631-635
Year:
2007
Laboratories:




 Record created 2007-06-13, last modified 2018-03-17


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