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  4. Quantitative Evaluation of Enhanced Multi-plane Clinical Fetal Diffusion MRI with a Crossing-Fiber Phantom
 
conference paper

Quantitative Evaluation of Enhanced Multi-plane Clinical Fetal Diffusion MRI with a Crossing-Fiber Phantom

Kebiri, Hamza
•
Lajous, Helene
•
Aleman-Gomez, Yasser
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January 1, 2021
Computational Diffusion Mri, Cdmri 2021
12th International Workshop on Computational Diffusion MRI (CDMRI)

Diffusion Magnetic Resonance Imaging (dMRI) has become widely used to study in vivo white matter tissue properties noninvasively. However, fetal dMRI is greatly limited in Signal-to-Noise ratio and spatial resolution. Due to the uncontrollable fetal motion, echo planar imaging acquisitions often result in highly degraded images, hence the ability to depict precise diffusion MR properties remains unknown. To the best of our knowledge, this is the first study to evaluate diffusion properties in a fetal customized crossing-fiber phantom. We assessed the effect of scanning settings on diffusion quantities in a phantom specifically designed to mimic typical values in the fetal brain. Orthogonal acquisitions based on clinical fetal brain schemes were preprocessed for denoising, bias field inhomogeneity and distortion correction. We estimated the fractional anisotropy (FA) and mean diffusivity (MD) from the diffusion tensor, and the fiber orientations from the fiber orientation distribution function. Quantitative evaluation was carried out on the number of diffusion gradient directions, different orthogonal acquisitions, and enhanced 4D volumes from scattered data interpolation of multiple series. We found out that while MD does not vary with the number of diffusion gradient directions nor the number of orthogonal series, FA is slightly more accurate with more directions. Additionally, errors in all scalar diffusion maps are reduced by using enhanced 4D volumes. Moreover, reduced fiber orientation estimation errors were obtained when used enhanced 4D volumes, but not with more diffusion gradient directions. From these results, we conclude that using enhanced 4D volumes from multiple series should be preferred over using more diffusion gradient directions in clinical fetal dMRI.

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Type
conference paper
DOI
10.1007/978-3-030-87615-9_2
Web of Science ID

WOS:000791040400002

Author(s)
Kebiri, Hamza
Lajous, Helene
Aleman-Gomez, Yasser
Girard, Gabriel  
Rodriguez, Erick Canales  
Tourbier, Sebastien
Pizzolato, Marco  
Ledoux, Jean-Baptiste
Fornari, Eleonora
Jakab, Andras
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Date Issued

2021-01-01

Publisher

SPRINGER INTERNATIONAL PUBLISHING AG

Publisher place

Cham

Published in
Computational Diffusion Mri, Cdmri 2021
ISBN of the book

978-3-030-87615-9

978-3-030-87614-2

Series title/Series vol.

Lecture Notes in Computer Science; 13006

Start page

12

End page

22

Subjects

Computer Science, Software Engineering

•

Computer Science, Theory & Methods

•

Computer Science

•

fetal

•

mri

•

brain

•

phantom

•

diffusion tensor imaging

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orientation distribution function

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scattered data interpolation

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histological validation

•

tractography

•

reconstruction

•

deconvolution

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LTS5  
Event nameEvent placeEvent date
12th International Workshop on Computational Diffusion MRI (CDMRI)

ELECTR NETWORK

Oct 01, 2021

Available on Infoscience
May 23, 2022
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/188105
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