research article

Synthesis of hapalosin and 8-deoxy-hapalosin

Wagner, Bjorn
•
Beugelmans, Rene
•
Zhu, Jieping  
1996
Tetrahedron Letters

Hapalosin, a new MDR reversing agent, and its congener 8-deoxyhapalosin have been synthesized via macrolactamization. A new procedure for selective N-methylation of a vicinal amino alc. is uncovered in the course of this study. [on SciFinder (R)]

Type
research article
DOI
10.1016/0040-4039(96)01415-3
Author(s)
Wagner, Bjorn
Beugelmans, Rene
Zhu, Jieping  
Date Issued

1996

Publisher

Elsevier

Published in
Tetrahedron Letters
Volume

37

Issue

36

Start page

6557

End page

6560

Subjects

Conformation and Conformers (synthesis of hapalosin and deoxyhapalosin)

•

hapalosin prepn; methylation vicinal amino alc

Note

CAN 125:301546

34-3

Amino Acids, Peptides, and Proteins

Inst. Chim. Substances Naturelles,CNRS,Gif-sur-Yvette,Fr.

Journal

written in English.

50-00-0 (Formaldehyde); 124-13-0 (Octanal); 13734-34-4; 56267-15-3; 65138-05-8; 101711-78-8 Role: RCT (Reactant), RACT (Reactant or reagent) (synthesis of hapalosin and deoxyhapalosin); 72155-47-6P; 112271-08-6P; 174623-90-6P; 182621-36-9P; 182621-37-0P; 182621-38-1P; 182621-40-5P; 182621-41-6P; 182621-43-8P; 182621-44-9P; 182621-45-0P; 182621-46-1P; 182822-93-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (synthesis of hapalosin and deoxyhapalosin); 159542-04-8P (Hapalosin); 182621-42-7P; 182621-47-2P Role: SPN (Synthetic preparation), PREP (Preparation) (synthesis of hapalosin and deoxyhapalosin)

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LSPN  
Available on Infoscience
November 25, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/58559