research article

Synthesis of model of phomopsin-ustiloxin-type antimitotic agents

Laib, Taoues
•
Zhu, Jieping  
2000
Synlett

An intramol. SNAr reaction was applied to the synthesis of a 13-membered meta-cyclophane that is the structural core of phomopsin and ustiloxin-type antimitotics. Two types of facile beta -elimination processes are also presented. [on SciFinder (R)]

Cite this item

Laib, T., & Zhu, J. (2000). Synthesis of model of phomopsin-ustiloxin-type antimitotic agents. Synlett, (9), 1363–1365. https://doi.org/10.1055/s-2000-7137

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Type
research article
DOI
10.1055/s-2000-7137
Author(s)
Laib, Taoues
Zhu, Jieping  
Date Issued

2000

Published in
Synlett
Issue

9

Start page

1363

End page

1365

Subjects

Cyclization (SNAr; prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); Mitosis (antimitotic agents; prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); Substitution reaction (arom.

•

intramol. cyclization; prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); Metacyclophanes Role: SPN (Synthetic preparation)

•

PREP (Preparation) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); Elimination reaction (beta -; prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins)

•

phomopsin ustiloxin metacyclophane structural core prepn

Note

CAN 134:17720

34-3

Amino Acids, Peptides, and Proteins

Institut de Chimie des Substances Naturelles, CNRS,Gif-sur-Yvette,Fr.

Journal

written in English.

309714-47-4P Role: BYP (Byproduct), PREP (Preparation) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); 64925-80-0 (Phomopsin A); 143557-93-1 (Ustiloxin A); 158243-18-6 (Ustiloxin D) Role: MSC (Miscellaneous) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); 141-43-5 (2-Hydroxyethylamine); 2788-84-3 (Methyl L-serinate); 4070-48-8 (Methyl L-valinate); 171978-33-9; 309714-51-0 Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); 309714-43-0P; 309714-44-1P; 309714-45-2P; 309714-48-5P; 309714-49-6P; 309714-50-9P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins); 309714-46-3P; 309714-52-1P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of meta-cyclophane structural cores of antimitotic phomopsins and ustiloxins)

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LSPN  
Available on Infoscience
November 25, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/58517