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  4. Toward efficient signal extraction for deep tissue blood flow using parallelized diffuse correlation spectroscopy
 
conference paper

Toward efficient signal extraction for deep tissue blood flow using parallelized diffuse correlation spectroscopy

Wu, Melissa M.
•
Kreiß, Lucas
•
Wayne, Michael
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Tuchin, Valery V.
•
Leahy, Martin J.
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March 20, 2025
Dynamics and Fluctuations in Biomedical Photonics XXII
Dynamics and Fluctuations in Biomedical Photonics XXII

Diffuse correlation spectroscopy (DCS) is an optical technique that allows for non-invasive measurements of tissue perfusion, and is often used for neuromonitoring applications. However, a major challenge of DCS is low SNR for deep tissue measurements. Recent works have demonstrated the potential for SPAD arrays to provide significant SNR increases by averaging autocorrelation signals from individual speckles. To fully exploit the potential of SPAD array signals, in this work we present alternative methods to recovering the desired blood flow signal and demonstrate their effectiveness in reducing the required sampling time or improving computation speed.

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Type
conference paper
DOI
10.1117/12.3043566
Author(s)
Wu, Melissa M.

Duke University

Kreiß, Lucas

Duke University

Wayne, Michael

Duke University

Bruschini, Claudio  

EPFL

Charbon, Edoardo  

EPFL

Horstmeyer, Roarke

Duke University

Editors
Tuchin, Valery V.
•
Leahy, Martin J.
•
Wang, Ruikang K.
Date Issued

2025-03-20

Publisher

SPIE

Published in
Dynamics and Fluctuations in Biomedical Photonics XXII
Series title/Series vol.

Proceedings SPIE; PC13318

Start page

10

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
AQUA  
Event nameEvent acronymEvent placeEvent date
Dynamics and Fluctuations in Biomedical Photonics XXII

San Francisco, United States

2025-01-25 - 2025-01-31

Available on Infoscience
December 23, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/257286
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