research article

Asymmetric synthesis of protected γ-carboxy-L-glutamic acid

Couturier, Cedric
•
Liron, Melanie
•
Schlama, Thierry
Show more
2005
Synlett

An asym. synthesis of an orthogonally protected gamma -carboxy-L-glutamic acid (L-Gla) is developed featuring a key proline-catalyzed Knoevenagel condensation between Garner's aldehyde and Meldrum's acid. [on SciFinder (R)]

Cite this item

Couturier, C., Liron, M., Schlama, T., & Zhu, J. (2005). Asymmetric synthesis of protected γ-carboxy-L-glutamic acid. Synlett, (5), 851–853. https://doi.org/10.1055/s-2005-863734

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Type
research article
DOI
10.1055/s-2005-863734
Author(s)
Couturier, Cedric
Liron, Melanie
Schlama, Thierry
Zhu, Jieping  
Date Issued

2005

Published in
Synlett
Issue

5

Start page

851

End page

853

Subjects

Asymmetric synthesis and induction; Knoevenagel reaction (asym. synthesis of protected gamma -carboxy-L-glutamic acid)

•

asym synthesis protected gamma carboxyglutamic acid; glutamic acid protected gamma carboxy asym synthesis

Note

CAN 143:26833

34-2

Amino Acids, Peptides, and Proteins

Institut de Chimie des Substances Naturelles,CNRS,Gif-sur-Yvette,Fr.

Journal

written in English.

609-36-9 (Proline); 13139-17-8 (N-Benzyloxycarbonyloxysuccinamide) Role: CAT (Catalyst use), USES (Uses) (asym. synthesis of protected gamma -carboxy-L-glutamic acid); 2033-24-1 (Meldrum's acid); 10065-72-2; 102308-32-7 (Garner's aldehyde) Role: RCT (Reactant), RACT (Reactant or reagent) (asym. synthesis of protected gamma -carboxy-L-glutamic acid); 852536-16-4P; 852536-19-7P; 852536-21-1P; 852536-25-5P; 852536-26-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (asym. synthesis of protected gamma -carboxy-L-glutamic acid); 181637-48-9P; 852536-27-7P; 852536-29-9P Role: SPN (Synthetic preparation), PREP (Preparation) (asym. synthesis of protected gamma -carboxy-L-glutamic acid)

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LSPN  
Available on Infoscience
November 25, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/58472