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  4. Characterisation of Polymer Materials for the Development of an Artificial Urethra
 
conference paper

Characterisation of Polymer Materials for the Development of an Artificial Urethra

De Menech, Quentin  
•
Andre, Loriane  
•
Konstantinidi, Stefania  
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2024
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
46 International Conference of the IEEE Engineering in Medicine and Biology Society

Low Urinary Tract Dysfunctions (LUTD) and in particular Urinary Incontinence (UI) is a medical condition affecting millions of people worldwide. In this context researchers and engineers performed tests on porcine and human urethras. However, ethical concerns and limited human tissue availability make direct testing on human urethras complicated. Consequently, animal testing, particularly on porcine urethras, has been explored due to their analogous dimensions, anatomical features, and tissue properties. Even though the use of porcine urethras is a good replacement of human urethras, it does not have exactly the same dimensions, mechanical properties and brings ethical concerns. In this paper we propose a replacement for porcine and human urethra testing by investigating several materials that could be used to develop an artificial urethra. Promising materials such as polymers from the silicone and hydrogel families are identified from our literature review. Then, experimental tests performed on an universal tensile test machine is detailed, including the manufacturing of several polymers for which the stress strain response were not well defined in existing literature. From our results, silicone Ecoflex 0010 and our custom made hydrogel polyacrylamide (PAAm) exhibit a stress strain relationship close to human urethra. Even though human urethra and the tested polymers demonstrate a non-linear behaviour, our results shows that our PAAm and Ecoflex 0010 have a maximum stress ranging from 2.2 to 20 kPa for a strain varying from 0 to 1. These materials are deemed suitable as an artificial urethra and a viable substitute for the human urethra.

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Type
conference paper
DOI
10.1109/EMBC53108.2024.10781661
Scopus ID

2-s2.0-85214994032

Author(s)
De Menech, Quentin  

École Polytechnique Fédérale de Lausanne

Andre, Loriane  

École Polytechnique Fédérale de Lausanne

Konstantinidi, Stefania  

École Polytechnique Fédérale de Lausanne

Benouhiba, Amine  

École Polytechnique Fédérale de Lausanne

Martinez, Thomas  

École Polytechnique Fédérale de Lausanne

Civet, Yoan  

École Polytechnique Fédérale de Lausanne

Baldit, Adrien

Université de Lorraine

Perriard, Yves  

École Polytechnique Fédérale de Lausanne

Date Issued

2024

Publisher

Institute of Electrical and Electronics Engineers Inc.

Published in
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISBN of the book

9798350371499

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
CAM-GE  
LAI  
Event nameEvent acronymEvent placeEvent date
46 International Conference of the IEEE Engineering in Medicine and Biology Society

Orlando, United States

2024-07-15 - 2024-07-19

Available on Infoscience
January 26, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/244973
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