A reliable procedure was developed for the synthesis of isocyano peptides by dehydration of the corresponding N-formyl derivs. with phosphoryl chloride in combination with triethylamine. The isocyano peptides were prepd. in excellent yields and with min. epimerization. [on SciFinder (R)]
Cite this item
Zhao, G., Bughin, C., Bienayme, H., & Zhu, J. (2003). Synthesis of isocyano peptides by dehydration of the N-formyl derivatives. Synlett, (8), 1153–1154. https://doi.org/10.1055/s-2003-39898
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2003
8
1153
1154
CAN 139:350927
34-3
Amino Acids, Peptides, and Proteins
Institut de Chimie des Substances Naturelles, CNRS,Gif-Sur-Yvette,Fr.
Journal
written in English.
4172-32-1; 619335-48-7; 619335-50-1; 619335-52-3; 619335-54-5; 619335-56-7; 619335-58-9; 619335-60-3 Role: RCT (Reactant), RACT (Reactant or reagent) (synthesis of isocyano peptides by dehydration of corresponding formyl derivs. with phosphoryl chloride); 59490-41-4P; 619335-46-5P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (synthesis of isocyano peptides by dehydration of corresponding formyl derivs. with phosphoryl chloride); 10025-87-3 (Phosphoryl chloride) Role: RGT (Reagent), RACT (Reactant or reagent) (synthesis of isocyano peptides by dehydration of corresponding formyl derivs. with phosphoryl chloride); 61752-36-1P; 619335-45-4P; 619335-47-6P; 619335-49-8P; 619335-51-2P; 619335-53-4P; 619335-55-6P; 619335-57-8P; 619335-59-0P; 619335-61-4P Role: SPN (Synthetic preparation), PREP (Preparation) (synthesis of isocyano peptides by dehydration of corresponding formyl derivs. with phosphoryl chloride)
REVIEWED
OTHER