Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods
A method and device for the rapid detection of biomolecules (320) diffusing in a nanometer-confined slit (204) is claimed. In particular, the present invention relates to a novel concept of fluidic side apertures (205) that facilitates the filling of the device, the surface coating with biomolecules and that measures the affinity between fluorescently labeled biomolecules in aqueous solution with other biomolecules immobilized on surfaces.
43639465
Alternative title(s) : (de) Nanofluidischer biosensor und seine verwendung zur schnellen messung von biomolekularen interaktionen in einer lösung und verfahren (fr) Biocapteur nanofluidique et son utilisation à des fins de mesure rapide d'interactions biomoléculaires en solution et procédés associés
TTO:6.0953
| DOI | Country code | Kind code | Date issued |
EP2504684 | EP | B1 | 2023-11-15 |
EP2504684 | EP | C0 | 2023-11-15 |
BR112012012787 | BR | B1 | 2019-12-17 |
CA2782009 | CA | C | 2017-10-03 |
US9452927 | US | B2 | 2016-09-27 |
BR112012012787 | BR | A2 | 2016-08-16 |
CN102762971 | CN | B | 2015-05-27 |
JP5685601 | JP | B2 | 2015-03-18 |
AU2010322751 | AU | B2 | 2014-05-29 |
HK1175527 | HK | A1 | 2013-07-05 |
JP2013512428 | JP | A | 2013-04-11 |
US2013017967 | US | A1 | 2013-01-17 |
CN102762971 | CN | A | 2012-10-31 |
EP2504684 | EP | A1 | 2012-10-03 |
AU2010322751 | AU | A1 | 2012-06-21 |
CA2782009 | CA | A1 | 2011-06-03 |
WO2011064701 | WO | A1 | 2011-06-03 |